Alzheimer’s Disease
A remarkable new study has moved scientists closer to preventing and curing age-related cognitive loss, particularly in Alzheimers disease and dementia in its early stages.
This ground-breaking study, which was published in the journal Aging on September 9th, is part of a larger programme investigating age-related cognitive decline. The study, led by Tel Aviv University and the Sagol School of Neuroscience, is the first to show that hyperbaric oxygen therapy (HBOT), a non-pharmaceutical technique, is successful in reversing the key activators and early signs of Alzheimers disease.
Alzheimer’s Disease
According to the Alzheimer’s Society, research conducted shows that, in 2019, there were over 850,000 people with dementia in the UK. This represents 1 in every 14 of the population aged 65 years and over. In 2040, there will be over 1.5 million people with dementia in the UK, at the current rate of prevalence.
HBOT is a type of oxygen therapy in which a patient is given 100% pure oxygen in a pressured environment. It’s been used to treat other conditions for decades, including non-healing ischemic wounds. It has also shown promising signs as a possible treatment for reversing the major activators and early signs of Alzheimer’s disease and dementia, as well as treating brain and cognitive impairments, for the first time.
Ageing and reduction
of blood flow
of blood flow
The brain is a huge, complicated entity that houses a vast network of nerve cells (neurons) that rely on oxygen to survive. The number of blood vessels in our brain typically decreases as we age. This results in decreased blood flow to the brain, which results in the brain receiving less oxygen. Vascular dysfunction, which occurs when blood flow is reduced, is a known precursor of Alzheimer’s disease, as are amyloid plaques.
Amyloid plaques are hard, insoluble protein clumps that grow in the gaps between your brain’s neurons. They have normally flushed away without consequence in a healthy brain. However, just as plaque can build up on your teeth if you don’t brush them regularly, the same thing can happen in your brain if you don’t clean it routinely.
The formation of amyloid plaques in the blood vessel walls of the brain becomes more susceptible as it matures. When an amyloid plaque forms, it can harm the brain’s neurons. These plaques are thought to play a role in Alzheimer’s disease progression and the cognitive impairment that comes with it.
For years, experts have debated whether or not amyloid plaques can be dissolved or shrunk. For the first time, a remarkable new study shows that a particular HBOT strategy can repair amyloid plaques and prevent them from accumulating in the first place.
Researchers first experimented with HBOT on mice to see how it affects amyloid plaques. Researchers delivered HBOT to a group of mice with amyloid plaques in their brains in the first stage of the study. For four weeks, the mice were given two 60-minute HBOT sessions per day, five days a week. HBOT effectively reduced the amyloid burden in the mice’s brains, reducing amyloid plaques by over 30% and shrinking plaques by about 19%, according to the researchers.
HBOT also prevented the creation of new amyloid plaques, and the mice performed better on cognitive activities when compared to the control group, indicating that HBOT improved their cognitive abilities.
HBOT can be utilised as both a therapeutic and a prevention measure for Alzheimer’s disease, according to a new study based on mice. The researchers subsequently attempted to apply the same procedure to human clinical trials.
Six patients, all over 70 years of age and suffering from minor cognitive impairment, made up the human test group. The patient’s cognitive functions improved significantly after getting 60 daily HBOT sessions over a three-month period, including enhanced memory recall, focus, and response times.
The ability of HBOT to boost blood flow in the brain is the reason for this. The brain receives more oxygen when it receives more blood. Furthermore, when the brain obtains more oxygen, it is able to work at its full potential.
What this means for Alzheimer’s Disease sufferers
The findings suggest that HBOT may be a viable drug-free therapy for preventing and treating Alzheimer’s disease, putting us one step closer to preventing and potentially reversing memory loss and mild cognitive impairment.
We’re laying the groundwork for Alzheimer’s prevention by treating vascular dysfunction. More research is being carried out by Pure Medicals clinical team to show how hyperbaric oxygen therapy (HBOT) can improve cognitive function and become a powerful tool in the fight against Alzheimer’s disease.
To evaluate progress and provide interdisciplinary clinical team support, the Pure Medical Program includes thorough testing and assessments before, during, and after the treatment protocol.
Alternative and Complementary therapies
for treating Alzheimer’s Disease Patients
Alzheimer’s Disease Treatment & Therapy
Scientific Studies
In this section, you will find an array of Alzheimer’s Disease Treatment & Therapy scientific case studies.
Hyperbaric Oxygen Therapy (HBOT)
Ronit Shapira, Amos Gdalyahu, Irit Gottfried, Efrat Sasson, Amir Hadanny, Shai Efrati, Pablo Blinder, Uri Ashery
Aging – 9 September 2021 – Volume 13, Issue 17 – pp 20935—20961
Hyperbaric Oxygen Therapy (HBOT)
Jianwen Chen, Feng Zhang, Li Zhao, Cheng Cheng, Rujia Zhong, Chunbo Dong, and Weidong Le
NCBI – 14 June 2020 – PMID: 32548235
Hyperbaric Oxygen Therapy (HBOT)
Tel Aviv University
30 September 2021 – Physicsworld – 203485
Hyperbaric Oxygen Therapy (HBOT)
Paul Harch, Edward Fogarty
Louisiana State University Health Sciences Center – 24 January 2019 – 190124124742
Hyperbaric Oxygen Therapy (HBOT)
Qiang You, Lan Li, Su-qin Xiong, Yu-fen Yan, Dan Li, Na-na Yan, Hong-ping Chen, and You-ping Liu
Frontiers in Aging Neuroscience – 17 April 2019 – ID: CRD42019117178
Cryotherapy
Blazej Misiak, Andrzej Kiejna
NCBI – July 2012 – PMID: 22541861
Cryotherapy
B.Stanczykiewicz, D.Szczesniak, J.Rymaszewska
ScienceDirect – European Psychiatry – June 2015 – Article: 1454
Blood Ozone Therapy
Catia Scassellati, Antonio Carlo Galoforo, Cristian Bonvicini, Ciro Esposito, and Giovanni Ricevuti
NCIB – November 2020 – PMID: 32810649
Photobiomodulation Therapy
Farzad Salehpour, Mahsa Khademi, Michael R Hamblin
NCIB – July 2021 – PMID: 33935090
Photobiomodulation Therapy
Marvin H Berman, Trent W Nichols
NCIB – October 2019 – PMID: 31647776
Photobiomodulation Therapy
Ann Liebert, Brian Bicknell, E-Liisa Laakso, Gillian Heller, Parastoo Jalilitabaei, Sharon Tilley, John Mitrofanis, Hosen Kiat
NCBI – July 2021 – PMID: 34215216
Photobiomodulation Therapy
Michael R. Hamblin
NCBI – September 2019 – PMID: 31363464
Infrared Sauna Therapy
Tanjaniina Laukkanen, Setor Kunutsor, Jussi Kauhanen, Jari Antero Laukkanen
NCBI – March 2017 – PMID: 27932366
Infrared Sauna Therapy
Andrew P. Hunt, Geoffrey M. Minett, Oliver R. Gibson, Graham K. Kerr and Ian B. Stewart
January 2020 – Frontiers In Physiology- 00.00001556
Alzheimer’s Disease
A remarkable new study has moved scientists closer to preventing and curing age-related cognitive loss, particularly in Alzheimer’s disease and dementia in its early stages.
This ground-breaking study, which was published in the journal Aging on September 9th, is part of a larger programme investigating age-related cognitive decline. The study, led by Tel Aviv University and the Sagol School of Neuroscience, is the first to show that hyperbaric oxygen therapy (HBOT), a non-pharmaceutical technique, is successful in reversing the key activators and early signs of Alzheimer’s disease.
According to the Alzheimer’s Society, research conducted shows that, in 2019, there were over 850,000 people with dementia in the UK. This represents 1 in every 14 of the population aged 65 years and over. In 2040, there will be over 1.5 million people with dementia in the UK, at the current rate of prevalence.
HBOT is a type of oxygen therapy in which a patient is given 100% pure oxygen in a pressured environment. It’s been used to treat other conditions for decades, including non-healing ischemic wounds. It has also shown promising signs as a possible treatment for reversing the major activators and early signs of Alzheimer’s disease and dementia, as well as treating brain and cognitive impairments, for the first time.
Ageing and reduction
of blood flow
of blood flow
The brain is a huge, complicated entity that houses a vast network of nerve cells (neurons) that rely on oxygen to survive. The number of blood vessels in our brain typically decreases as we age. This results in decreased blood flow to the brain, which results in the brain receiving less oxygen. Vascular dysfunction, which occurs when blood flow is reduced, is a known precursor of Alzheimer’s disease, as are amyloid plaques.
Amyloid plaques are hard, insoluble protein clumps that grow in the gaps between your brain’s neurons. They have normally flushed away without consequence in a healthy brain. However, just as plaque can build up on your teeth if you don’t brush them regularly, the same thing can happen in your brain if you don’t clean it routinely.
The formation of amyloid plaques in the blood vessel walls of the brain becomes more susceptible as it matures. When an amyloid plaque forms, it can harm the brain’s neurons. These plaques are thought to play a role in Alzheimer’s disease progression and the cognitive impairment that comes with it.
For years, experts have debated whether or not amyloid plaques can be dissolved or shrunk. For the first time, a remarkable new study shows that a particular HBOT strategy can repair amyloid plaques and prevent them from accumulating in the first place.
Researchers first experimented with HBOT on mice to see how it affects amyloid plaques. Researchers delivered HBOT to a group of mice with amyloid plaques in their brains in the first stage of the study. For four weeks, the mice were given two 60-minute HBOT sessions per day, five days a week. HBOT effectively reduced the amyloid burden in the mice’s brains, reducing amyloid plaques by over 30% and shrinking plaques by about 19%, according to the researchers.
HBOT also prevented the creation of new amyloid plaques, and the mice performed better on cognitive activities when compared to the control group, indicating that HBOT improved their cognitive abilities.
HBOT can be utilised as both a therapeutic and a prevention measure for Alzheimer’s disease, according to a new study based on mice. The researchers subsequently attempted to apply the same procedure to human clinical trials.
Six patients, all over 70 years of age and suffering from minor cognitive impairment, made up the human test group. The patient’s cognitive functions improved significantly after getting 60 daily HBOT sessions over a three-month period, including enhanced memory recall, focus, and response times.
The ability of HBOT to boost blood flow in the brain is the reason for this. The brain receives more oxygen when it receives more blood. Furthermore, when the brain obtains more oxygen, it is able to work at its full potential.
What this means for Alzheimer’s Disease sufferers
The findings suggest that HBOT may be a viable drug-free therapy for preventing and treating Alzheimer’s disease, putting us one step closer to preventing and potentially reversing memory loss and mild cognitive impairment.
We’re laying the groundwork for Alzheimer’s prevention by treating vascular dysfunction. More research is being carried out by the Pure Medicals clinical team to show how hyperbaric oxygen therapy (HBOT) can improve cognitive function and become a powerful tool in the fight against Alzheimer’s disease.
To evaluate progress and provide interdisciplinary clinical team support, the Pure Medical Program includes thorough testing and assessments before, during, and after the treatment protocol.
Treatments & therapies Pure Medical use
when treating Alzheimer’s Disease Patients
Alzheimer’s Disease Treatment & Therapy
Scientific Studies
In this section, you will find an array of Alzheimer’s Disease Treatment & Therapy scientific case studies.
Hyperbaric Oxygen Therapy (HBOT)
Ronit Shapira, Amos Gdalyahu, Irit Gottfried, Efrat Sasson, Amir Hadanny, Shai Efrati, Pablo Blinder, Uri Ashery
Aging – 9 September 2021 – Volume 13, Issue 17 – pp 20935—20961
Hyperbaric Oxygen Therapy (HBOT)
Jianwen Chen, Feng Zhang, Li Zhao, Cheng Cheng, Rujia Zhong, Chunbo Dong, and Weidong Le
NCBI – 14 June 2020 – PMID: 32548235
Hyperbaric Oxygen Therapy (HBOT)
Tel Aviv University
30 September 2021 – Physicsworld – 203485
Hyperbaric Oxygen Therapy (HBOT)
Paul Harch, Edward Fogarty
Louisiana State University Health Sciences Center – 24 January 2019 – 190124124742
Hyperbaric Oxygen Therapy (HBOT)
Qiang You, Lan Li, Su-qin Xiong, Yu-fen Yan, Dan Li, Na-na Yan, Hong-ping Chen, and You-ping Liu
Frontiers in Aging Neuroscience – 17 April 2019 – ID: CRD42019117178
Cryotherapy
Blazej Misiak, Andrzej Kiejna
NCBI – July 2012 – PMID: 22541861
Cryotherapy
B.Stanczykiewicz, D.Szczesniak, J.Rymaszewska
ScienceDirect – European Psychiatry – June 2015 – Article: 1454
Blood Ozone Therapy
Catia Scassellati, Antonio Carlo Galoforo, Cristian Bonvicini, Ciro Esposito, and Giovanni Ricevuti
NCIB – November 2020 – PMID: 32810649
Photo-biomodulation Therapy
Farzad Salehpour, Mahsa Khademi, Michael R Hamblin
NCIB – July 2021 – PMID: 33935090
Photo-biomodulation Therapy
Marvin H Berman, Trent W Nichols
NCIB – October 2019 – PMID: 31647776
Photo-biomodulation Therapy
Ann Liebert, Brian Bicknell, E-Liisa Laakso, Gillian Heller, Parastoo Jalilitabaei, Sharon Tilley, John Mitrofanis, Hosen Kiat
NCBI – July 2021 – PMID: 34215216
Photo-biomodulation Therapy
Michael R. Hamblin
NCBI – September 2019 – PMID: 31363464
Infrared Sauna Therapy
Tanjaniina Laukkanen, Setor Kunutsor, Jussi Kauhanen, Jari Antero Laukkanen
NCBI – March 2017 – PMID: 27932366
Infrared Sauna Therapy
Andrew P. Hunt, Geoffrey M. Minett, Oliver R. Gibson, Graham K. Kerr and Ian B. Stewart
January 2020 – Frontiers In Physiology- 00.00001556